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1. Broussard CN, Richter JE. Nausea and vomiting of pregnancy, Gastroenterol Clin North Am. 1998;27: 123-51.
2. Kolasa KM, Weismiller DG. Nutrition during pregnancy. Am Fam Physician. 1997;56:206-212.
3. Emelianova S, Mazzotta P, Einarson A, Koren G. Prevalence and severity of nausea and vomiting of pregnancy and effect of vitamin supplementation. Clin Invest Med. 1999;22:106-110.
4. National Vital Statistics Reports, CDC Volume 52, Number 7 October 31, 2003.
5. Erick M. Hyperemesis gravidarum: a practical management strategy. OBG Management. November 2000;25-35.
6. Tierson FD, Olsen CL, Hook EB. Nausea and vomiting of pregnancy: a randomized double-blind placebo-controlled study. Am J Obstet Gynecol. 1986;155:1017-22.
7. Sahakian V, Rouse D, Sipes S, Rose N, Niebyl J. Vitamin B6 is effective therapy for nausea and vomiting of pregnancy: a randomized, double-blind placebo-controlled study. Obstet Gynecol. 1991;78:33- 36.
8. IMS NPA-TRx Prescription Data- 12 months ending February 2005. Includes PreCare® Prenatal, PrimaCare®, PrimaCare® ONE, PreCare® Chewables, PremesisRx®, and PreCare Concieve®.
9. Gilbert S.The ABCs of vitamins: vitamin B.Available at: http://health.ivillage.com/eating/evitamins/0,,68-p,00.html. Accessed April 12, 2005.
10. Lawson W.Vitamin B: a key to more energy. Psychology Today [serial online]. Available at: http://cms.psychologytoday.com/articles/pto-20030402-000005.html. Accessed May 13, 2005.
11. Prenate EliteTM prescribing information, First Horizon Pharmaceutical® Corporation, December 2004
12. OptiNateTM prescribing information, First Horizon Pharmaceutical® Corporation, December 2004.
13. Duet®DHA prescribing information, XanodyneTM Pharmaceuticals, Inc., 2003.
14. Data on File, Ther-Rx Corporation.
15. Wald NJ. Folic acid and the prevention of neural-tube defects. N Engl J Med. 2004;350:101-103.
16. Rimm EB,Willett WC, Hu FB, et al. Folate and vitamin B6 from diet and supplements in relation to coronary heart disease among women. JAMA. 1998;279:359-364.
17. Home pharmacy. eMedicine Consumer Health Web site. Available at: http://www.emedicinehealth.com/fulltext/11958.htm. Accessed 5/13/05.
18. Prenatal health, exams and procedures. University of Michigan Medical Center website. http://www.med.umich.edu/1libr/wha/wha_pgtest_crs.htm. Accessed on 5/5/05.
19. Pregnancy: Eating Right While Pregnant. WebMD website. http://my.webmd.com/content/article/51/40816.htm. Accessed on 5/5/05.
20. Pregnant Women Can Exercise More, Fly Longer, says ACOG. ACOG website. http://www.acog.org/from_home/publications/press_releases/nr12-12-01.cfm. Accessed 5/5/05.
21. Laurence KM, et al. Double-blind randomized controlled trial of folate treatment before conception to prevent recurrence of neural-tube defects. Br Med J. 1981;282:1509-11.
22. MRC Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet. 1991;338:131-7.
23. Czeizel AE, Dudas I. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med. 1992;327:1832-5.
24. Kirke PN, et al. A randomised trial of low dose folic acid to prevent neural tube defects. Arch Dis Child. 1992;67:1442-6.
25. Berry RJ, et al. Prevention of neural-tube defects with folic acid in China. N Engl J Med. 1999;341:1485-90. 11. Mulinare J, et al.
26. Bower C, Stanley FJ. Dietary folate as a risk factor for neural-tube defects: evidence from a case-control study in Western Australia. Med J Aust. 1989;150:613-9.
27. Mills JL, et al. The absence of a relation between the periconceptional use of vitamins and neural-tube defects. N Engl J Med. 1989;321:430-5.
28. Milunsky A, et al. Multivitamin/folic acid supplementation in early pregnancy reduces the prevalence of neural tube defects. JAMA. 1989;262:2847-52.
29. Werler MM, et al. Periconceptional folic acid exposure and risk of occurrent neural tube defects. JAMA. 1993;269:1257-61.
30. Shaw GM, et al. Risks of orofacial clefts in children born to women using multivitamins containing folic acid periconceptionially. Lancet. 1995;345:393-6.
31. Wilson RD, et al. The use of folic acid for the prevention of neural tube defects and other congenital anomalies. J Obstet Gynaecol Can . 2003;25:959-65.
32. Pentieva K, et al. The short-term bioavailabilities of [6S]-5-methyltetrahydrofolate and folic acid are equivalent in men. J Nutr. 2004;134:580-5
33. Among nutritional supplements.
34.

The good the bad and the ugly: The third trimester. WebMD website. http://www.webmd.com/content/Article/88/99724.htm?pagenumber=2. Accessed on 2/22/06.

 
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